CLINICAL OUTCOMES

Relapse

Glossary · Published 2026-05-18 · Last reviewed 2026-09-23

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Canonical definition

Relapse is the return of symptoms after a period of improvement or recovery. It's common across many conditions and is best treated as a setback to manage, not a personal failure.

Definition from Shrinktionary, reviewed by Shariq Refai, MD, MBA, FAPA (last reviewed 2026-06-26). Shrinktionary is the network's language layer and carries the canonical short definition; this page adds the research-context detail below. Full definition on Shrinktionary →

In more detail

Getting better once isn't the end of the story. Anxiety disorders can come back. Relapse means symptoms have returned to the point of meeting the diagnosis again, after the person had improved. It is different from a brief bad day or a short rough patch.

Why it matters in anxiety research

Relapse is why follow-up length matters so much in anxiety trials. A study that ends at twelve weeks shows whether a treatment works in the short term. It says nothing about whether the benefit lasts. Research that follows people for a year or more is far more informative about relapse.

An example

A trial finds that many people reach remission with medication. After the trial, some stop the medication and their symptoms return. That return is relapse, and it's a common reason clinicians discuss continuing treatment past the point of feeling better.

What to watch for

A short trial can't speak to relapse at all. When a treatment is described as durable or lasting, check how long the study actually followed people. Relapse rates also depend on whether treatment continued or stopped.

Related terms

Related reports or summaries

Related on this site

Why outcomes vary between individuals; Treatment adherence research

Source

APA Dictionary of Psychology, "relapse." https://dictionary.apa.org/

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